![Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study - Zhou - ESC Heart Failure - Wiley Online Library Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study - Zhou - ESC Heart Failure - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/b55d8232-fd2d-4bb1-b500-979030cd234d/ehf214068-fig-0004-m.jpg)
Targeting efficacy of spironolactone in patients with heart failure with preserved ejection fraction: the TOPCAT study - Zhou - ESC Heart Failure - Wiley Online Library
![Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations | JACC: Basic to Translational Science Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations | JACC: Basic to Translational Science](https://www.jacc.org/cms/asset/d7cf7bd7-e4b1-45fe-a3e0-05c93e492acf/gr3.jpg)
Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations | JACC: Basic to Translational Science
![Under-Enrollment of Obese Heart Failure with Preserved Ejection Fraction Patients in Major HFpEF Clinical Trials - Journal of Cardiac Failure Under-Enrollment of Obese Heart Failure with Preserved Ejection Fraction Patients in Major HFpEF Clinical Trials - Journal of Cardiac Failure](https://www.onlinejcf.com/cms/asset/ffe16d7d-fcb7-4312-b976-4cf3ee3bf261/gr1.jpg)
Under-Enrollment of Obese Heart Failure with Preserved Ejection Fraction Patients in Major HFpEF Clinical Trials - Journal of Cardiac Failure
Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Protocols
![Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations - ScienceDirect Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2452302X16000346-gr1.jpg)
Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations - ScienceDirect
![Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial | Circulation Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial | Circulation](https://www.ahajournals.org/cms/asset/ee723c25-9e17-4d89-9603-243a0a3b3888/34fig01.jpeg)
Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial | Circulation
![Spectrum of epidemiological and clinical findings in patients with heart failure with preserved ejection fraction stratified by study design: a systematic review - Vaduganathan - 2016 - European Journal of Heart Failure - Wiley Online Library Spectrum of epidemiological and clinical findings in patients with heart failure with preserved ejection fraction stratified by study design: a systematic review - Vaduganathan - 2016 - European Journal of Heart Failure - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/82a89083-68c3-4c8b-b0c5-7b352140ef5b/ejhf442-fig-0001-m.jpg)
Spectrum of epidemiological and clinical findings in patients with heart failure with preserved ejection fraction stratified by study design: a systematic review - Vaduganathan - 2016 - European Journal of Heart Failure - Wiley Online Library
![Rates of Spironolactone Initiation and Subsequent Hyperkalemia Hospitalizations in Patients with Heart Failure with Preserved Ejection Fraction Following the TOPCAT trial: A Cohort Study of Medicare Beneficiaries - Journal of Cardiac Failure Rates of Spironolactone Initiation and Subsequent Hyperkalemia Hospitalizations in Patients with Heart Failure with Preserved Ejection Fraction Following the TOPCAT trial: A Cohort Study of Medicare Beneficiaries - Journal of Cardiac Failure](https://www.onlinejcf.com/cms/asset/3f45bb32-024d-4462-912c-bcb42a08270e/gr1.jpg)
Rates of Spironolactone Initiation and Subsequent Hyperkalemia Hospitalizations in Patients with Heart Failure with Preserved Ejection Fraction Following the TOPCAT trial: A Cohort Study of Medicare Beneficiaries - Journal of Cardiac Failure
Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Manual of Operations
![Abstract 14199: Defining Phenotypic Representativeness of the TOPCAT Trial to a Real-World Electronic Health Record Using Multidimensional Phenomaps | Circulation Abstract 14199: Defining Phenotypic Representativeness of the TOPCAT Trial to a Real-World Electronic Health Record Using Multidimensional Phenomaps | Circulation](https://www.ahajournals.org/cms/asset/ce8acf72-85b8-4cf3-a850-740e0959a119/g14199.jpg)
Abstract 14199: Defining Phenotypic Representativeness of the TOPCAT Trial to a Real-World Electronic Health Record Using Multidimensional Phenomaps | Circulation
![Prognostic Importance of Temporal Changes in Resting Heart Rate in Heart Failure and Preserved Ejection Fraction: From the TOPCAT Study | JACC: Heart Failure Prognostic Importance of Temporal Changes in Resting Heart Rate in Heart Failure and Preserved Ejection Fraction: From the TOPCAT Study | JACC: Heart Failure](https://www.jacc.org/cms/asset/a979d2b9-979a-4c8a-aaff-c00fc266e659/fx1.jpg)
Prognostic Importance of Temporal Changes in Resting Heart Rate in Heart Failure and Preserved Ejection Fraction: From the TOPCAT Study | JACC: Heart Failure
![PDF) C2HEST score predicts clinical outcomes in heart failure with preserved ejection fraction: a secondary analysis of the TOPCAT trial PDF) C2HEST score predicts clinical outcomes in heart failure with preserved ejection fraction: a secondary analysis of the TOPCAT trial](https://i1.rgstatic.net/publication/349410632_C2HEST_score_predicts_clinical_outcomes_in_heart_failure_with_preserved_ejection_fraction_a_secondary_analysis_of_the_TOPCAT_trial/links/602e9d1792851c4ed5803527/largepreview.png)
PDF) C2HEST score predicts clinical outcomes in heart failure with preserved ejection fraction: a secondary analysis of the TOPCAT trial
![Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations - ScienceDirect Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2452302X16000346-gr3.jpg)
Detection and Management of Geographic Disparities in the TOPCAT Trial: Lessons Learned and Derivative Recommendations - ScienceDirect
![Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial - ScienceDirect Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2213177918303718-gr1.jpg)
Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial - ScienceDirect
![Assessing the Eligibility Criteria in Phase III Randomized Controlled Trials of Drug Therapy in Heart Failure With Preserved Ejection Fraction: The Critical Play-Off Between a “Pure” Patient Phenotype and the Generalizability of Assessing the Eligibility Criteria in Phase III Randomized Controlled Trials of Drug Therapy in Heart Failure With Preserved Ejection Fraction: The Critical Play-Off Between a “Pure” Patient Phenotype and the Generalizability of](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/2100999198/2079823207/yjcaf3942-fig-0001.jpg)
Assessing the Eligibility Criteria in Phase III Randomized Controlled Trials of Drug Therapy in Heart Failure With Preserved Ejection Fraction: The Critical Play-Off Between a “Pure” Patient Phenotype and the Generalizability of
![Clinical information from repeated blood pressure measurements in the management of heart failure with preserved ejection fraction | Hypertension Research Clinical information from repeated blood pressure measurements in the management of heart failure with preserved ejection fraction | Hypertension Research](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41440-022-01079-9/MediaObjects/41440_2022_1079_Figa_HTML.png)
Clinical information from repeated blood pressure measurements in the management of heart failure with preserved ejection fraction | Hypertension Research
![Data-driven identification of heart failure disease states and progression pathways using electronic health records | Scientific Reports Data-driven identification of heart failure disease states and progression pathways using electronic health records | Scientific Reports](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41598-022-22398-4/MediaObjects/41598_2022_22398_Fig1_HTML.png)
Data-driven identification of heart failure disease states and progression pathways using electronic health records | Scientific Reports
![Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial | Circulation Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial | Circulation](https://www.ahajournals.org/cms/asset/199097bb-c29e-4902-a97a-168febccb5cf/34fig02.jpeg)